A Bimodal Distribution of Two Distinct Categories of Intrinsically Disordered Structures with Separate Functions in FG Nucleoporins

Nuclear pore complexes (NPCs) gate the only conduits for nucleocytoplasmic transport in eukaryotes. Their gate is formed by nucleoporins containing large intrinsically disordered domains with multiple phenylalanine-glycine repeats (FG domains). In combination, these are hypothesized to form a struct...

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Detalhes bibliográficos
Main Authors: Yamada, Justin, Phillips, Joshua L., Patel, Samir, Goldfien, Gabriel, Calestagne-Morelli, Alison, Huang, Hans, Reza, Ryan, Acheson, Justin, Krishnan, Viswanathan V., Newsam, Shawn, Gopinathan, Ajay, Lau, Edmond Y., Colvin, Michael E., Uversky, Vladimir N., Rexach, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953916/
https://ncbi.nlm.nih.gov/pubmed/20368288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M000035-MCP201
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