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Physical Motif Clustering within Intrinsically Disordered Nucleoporin Sequences Reveals Universal Functional Features

Bioinformatics of disordered proteins is especially challenging given high mutation rates for homologous proteins and that functionality may not be strongly related to sequence. Here we have performed a novel bioinformatic analysis, based on the spatial clustering of physically relevant features suc...

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Bibliografski detalji
Glavni autori: Ando, David, Colvin, Michael, Rexach, Michael, Gopinathan, Ajay
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774778/
https://ncbi.nlm.nih.gov/pubmed/24066078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073831
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