Regulation of the F11, Klkb1, Cyp4v3 Gene Cluster in Livers of Metabolically Challenged Mice

Single nucleotide polymorphisms (SNPs) in a 4q35.2 locus that harbors the coagulation factor XI (F11), prekallikrein (KLKB1), and a cytochrome P450 family member (CYP4V2) genes are associated with deep venous thrombosis (DVT). These SNPs exert their effect on DVT by modifying the circulating levels...

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Detalhes bibliográficos
Main Authors: Safdar, Huma, Cleuren, Audrey C. A., Cheung, Ka Lei, Gonzalez, Frank J., Vos, Hans L., Inoue, Yusuke, Reitsma, Pieter H., van Vlijmen, Bart J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774739/
https://ncbi.nlm.nih.gov/pubmed/24066149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074637
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