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Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1

Inhibitors of acyl CoA:cholesterol acyltransferase (ACAT) have attracted considerable interest as a potential treatment for atherosclerosis. Currently available inhibitors probably act nonselectively against the two known ACATs. One of these enzymes, ACAT1, is highly expressed in macrophages in athe...

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Bibliografski detalji
Glavni autori: Accad, Michel, Smith, Steven J., Newland, Dale L., Sanan, David A., King, Lloyd E., Linton, MacRae F., Fazio, Sergio, Farese, Robert V.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC377465/
https://ncbi.nlm.nih.gov/pubmed/10727439
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