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Prostaglandin G/H synthase-2 is required for maximal formation of osteoclast-like cells in culture
We examined the effect on osteoclast formation of disrupting the prostaglandin G/H synthase genes PGHS-1 and-2. Prostaglandin E(2) (PGE(2)) production was significantly reduced in marrow cultures from mice lacking PGHS-2 (PGHS-2(–/–)) compared with wild-type (PGHS-2(+/+)) cultures. Osteoclast format...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2000
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC377461/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10727451/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8195 |
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