Loading...

Prostaglandin G/H synthase-2 is required for maximal formation of osteoclast-like cells in culture

We examined the effect on osteoclast formation of disrupting the prostaglandin G/H synthase genes PGHS-1 and-2. Prostaglandin E(2) (PGE(2)) production was significantly reduced in marrow cultures from mice lacking PGHS-2 (PGHS-2(–/–)) compared with wild-type (PGHS-2(+/+)) cultures. Osteoclast format...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Okada, Yosuke, Lorenzo, Joseph A., Freeman, Amanda M., Tomita, Masato, Morham, Scott G., Raisz, Lawrence G., Pilbeam, Carol C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC377461/
https://ncbi.nlm.nih.gov/pubmed/10727451
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!