Bone morphogenetic protein 2 enhances PGE(2) stimulated osteoclast formation in murine bone marrow cultures

Bone morphogenetic protein 2 (BMP-2) is used clinically to stimulate bone formation and accelerate fracture repair. Adding prostaglandin (PG) E(2) or PGE(2) receptor agonists to BMP-2 has been proposed to improve BMP-2 efficacy. However, this may enhance bone resorption, since PGE(2) can increase re...

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Autores principales: Blackwell, Katherine A., Hortschansky, Peter, Sanovic, Srdan, Choudhary, Shilpa, Raisz, Lawrence G., Pilbeam, Carol C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783417/
https://ncbi.nlm.nih.gov/pubmed/19744575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2009.08.005
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