NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease

An oxidant-antioxidant imbalance in the lung contributes to the development of chronic obstructive pulmonary disease (COPD) that is caused by a complex interaction of genetic and environmental risk factors. Nuclear erythroid 2-related factor 2 (NFE2L2 or NRF2) is a critical molecule in the lung'...

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Autors principals: Sandford, Andrew J., Malhotra, Deepti, Boezen, H. Marike, Siedlinski, Mateusz, Postma, Dirkje S., Wong, Vivien, Akhabir, Loubna, He, Jian-Qing, Connett, John E., Anthonisen, Nicholas R., Paré, Peter D., Biswal, Shyam
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774584/
https://ncbi.nlm.nih.gov/pubmed/22693272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00027.2012
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