Polymorphisms in the ß(2) adrenergic receptor and bronchodilator response, bronchial hyperresponsiveness, and rate of decline in lung function in smokers

Methods: The prevalence of two ADRB2 polymorphisms, Arg16→Gly and Gln27→Glu, was examined in 587 smokers chosen from the NHLBI Lung Health Study for having the fastest (n=282) and slowest (n=305) 5 year rate of decline in forced expiratory volume in 1 second (FEV(1); mean ΔFEV(1) -4.14 and +1.08% pr...

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Detalhes bibliográficos
Main Authors: Joos, L, Weir, T, Connett, J, Anthonisen, N, Woods, R, Pare, P, Sandford, A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2003
Assuntos:
Smoking
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1746784/
https://ncbi.nlm.nih.gov/pubmed/12885990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thorax.58.8.703
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