Expression of Na(+)-d-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences

With a novel antibody against the rat Na(+)-d-glucose cotransporter SGLT2 (rSGLT2-Ab), which does not cross-react with rSGLT1 or rSGLT3, the ∼75-kDa rSGLT2 protein was localized to the brush-border membrane (BBM) of the renal proximal tubule S1 and S2 segments (S1 > S2) with female-dominant expre...

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Bibliographic Details
Main Authors: Sabolić, Ivan, Vrhovac, Ivana, Eror, Daniela Balen, Gerasimova, Maria, Rose, Michael, Breljak, Davorka, Ljubojević, Marija, Brzica, Hrvoje, Sebastiani, Anne, Thal, Serge C., Sauvant, Christoph, Kipp, Helmut, Vallon, Volker, Koepsell, Hermann
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Membrane Transporters, Ion Channels and Pumps
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774553/
https://ncbi.nlm.nih.gov/pubmed/22262063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00450.2011
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