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Expression profiling and immunolocalization of Na(+)-d-glucose-cotransporter 1 in mice employing knockout mice as specificity control indicate novel locations and differences between mice and rats

The expression and localization of sodium-d-glucose cotransporter SGLT1 (SLC5A1), which is involved in small intestinal glucose absorption and renal glucose reabsorption, is of high biomedical relevance because SGLT1 inhibitors are currently tested for antidiabetic therapy. In human and rat organs,...

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Bibliografiske detaljer
Udgivet i:Pflugers Arch
Main Authors: Madunić, Ivana Vrhovac, Breljak, Davorka, Karaica, Dean, Koepsell, Hermann, Sabolić, Ivan
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691098/
https://ncbi.nlm.nih.gov/pubmed/28842746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-017-2056-1
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