Loss of Endometrial Sodium Glucose Cotransporter SGLT1 is Detrimental to Embryo Survival and Fetal Growth in Pregnancy

Embryo implantation requires a hospitable uterine environment. A key metabolic change that occurs during the peri-implantation period, and throughout early pregnancy, is the rise in endometrial glycogen content. Glycogen accumulation requires prior cellular uptake of glucose. Here we show that both...

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Publicado no:Sci Rep
Main Authors: Salker, Madhuri S., Singh, Yogesh, Zeng, Ni, Chen, Hong, Zhang, Shaqiu, Umbach, Anja T, Fakhri, Hajar, Kohlhofer, Ursula, Quintanilla-Martinez, Leticia, Durairaj, Ruban R. Peter, Barros, Flavio S. V., Vrljicak, Pavle, Ott, Sascha, Brucker, Sara Y, Wallwiener, Diethelm, Vrhovac Madunić, Ivana, Breljak, Davorka, Sabolić, Ivan, Koepsell, Hermann, Brosens, Jan J., Lang, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5626729/
https://ncbi.nlm.nih.gov/pubmed/28974690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11674-3
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