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Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice

Cystic fibrosis (CF) mouse models exhibit exocrine pancreatic function, yet they do not develop adipose stores to the levels of non-CF mice. CF mice homozygous for the Cftr mutation (F508del) at 3 wk (postweaning) and 6 wk (young adult) of age had markedly less adipose tissue than non-CF mice. Food...

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Detaylı Bibliyografya
Asıl Yazarlar: Bederman, Ilya, Perez, Aura, Henderson, Leigh, Freedman, Joshua A., Poleman, James, Guentert, Dana, Ruhrkraut, Nicholas, Drumm, Mitchell L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774510/
https://ncbi.nlm.nih.gov/pubmed/22679004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00451.2011
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