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Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice

Cystic fibrosis (CF) mouse models exhibit exocrine pancreatic function, yet they do not develop adipose stores to the levels of non-CF mice. CF mice homozygous for the Cftr mutation (F508del) at 3 wk (postweaning) and 6 wk (young adult) of age had markedly less adipose tissue than non-CF mice. Food...

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Detalhes bibliográficos
Main Authors: Bederman, Ilya, Perez, Aura, Henderson, Leigh, Freedman, Joshua A., Poleman, James, Guentert, Dana, Ruhrkraut, Nicholas, Drumm, Mitchell L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774510/
https://ncbi.nlm.nih.gov/pubmed/22679004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00451.2011
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