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Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling

Nicotinamide phosphoribosyltransferase (Nampt) is an important coenzyme involved in cellular redox reactions. Inside the cell, Nampt (iNampt) functions as a rate-limiting enzyme in the NAD salvage pathway, and outside the cell (eNampt), it acts as a proinflammatory cytokine. High-circulating levels...

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Detalhes bibliográficos
Main Authors: Pillai, Vinodkumar B., Sundaresan, Nagalingam R., Kim, Gene, Samant, Sadhana, Moreno-Vinasco, Liliana, Garcia, Joe G. N., Gupta, Mahesh P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774498/
https://ncbi.nlm.nih.gov/pubmed/23203961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00468.2012
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