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Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling

Nicotinamide phosphoribosyltransferase (Nampt) is an important coenzyme involved in cellular redox reactions. Inside the cell, Nampt (iNampt) functions as a rate-limiting enzyme in the NAD salvage pathway, and outside the cell (eNampt), it acts as a proinflammatory cytokine. High-circulating levels...

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Bibliografske podrobnosti
Main Authors: Pillai, Vinodkumar B., Sundaresan, Nagalingam R., Kim, Gene, Samant, Sadhana, Moreno-Vinasco, Liliana, Garcia, Joe G. N., Gupta, Mahesh P.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774498/
https://ncbi.nlm.nih.gov/pubmed/23203961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00468.2012
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