Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling

Nicotinamide phosphoribosyltransferase (Nampt) is an important coenzyme involved in cellular redox reactions. Inside the cell, Nampt (iNampt) functions as a rate-limiting enzyme in the NAD salvage pathway, and outside the cell (eNampt), it acts as a proinflammatory cytokine. High-circulating levels...

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Détails bibliographiques
Auteurs principaux: Pillai, Vinodkumar B., Sundaresan, Nagalingam R., Kim, Gene, Samant, Sadhana, Moreno-Vinasco, Liliana, Garcia, Joe G. N., Gupta, Mahesh P.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2013
Sujets:
Signaling and Stress Response
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774498/
https://ncbi.nlm.nih.gov/pubmed/23203961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00468.2012
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