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SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70

There are seven SIRT isoforms in mammals, with diverse biological functions including gene regulation, metabolism, and apoptosis. Among them, SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans. In this study, we examined the role of...

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Autors principals: Sundaresan, Nagalingam R., Samant, Sadhana A., Pillai, Vinodkumar B., Rajamohan, Senthilkumar B., Gupta, Mahesh P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577434/
https://ncbi.nlm.nih.gov/pubmed/18710944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00426-08
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