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Kdm4b Histone Demethylase Is a DNA Damage Response Protein and Confers a Survival Advantage following γ-Irradiation

DNA damage evokes a complex and highly coordinated DNA damage response (DDR) that is integral to the suppression of genomic instability. Double-strand breaks (DSBs) are considered the most deleterious form damage. Evidence suggests that trimethylation of histone H3 lysine 9 (H3K9me3) presents a barr...

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Detalhes bibliográficos
Main Authors: Young, Leah C., McDonald, Darin W., Hendzel, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774405/
https://ncbi.nlm.nih.gov/pubmed/23744078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.491514
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