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Differential Contribution of Insulin and Amino Acids to the mTORC1-Autophagy Pathway in the Liver and Muscle

Autophagy is a highly inducible intracellular degradation process. It is generally induced by nutrient starvation and suppressed by food intake. Mammalian (or mechanistic) target of rapamycin complex 1 (mTORC1) is considered to be the major regulator of autophagy, but the precise mechanism of in viv...

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Bibliografiske detaljer
Main Authors: Naito, Takako, Kuma, Akiko, Mizushima, Noboru
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774374/
https://ncbi.nlm.nih.gov/pubmed/23744068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.456228
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