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Ten-Eleven Translocation 1 (Tet1) Is Regulated by O-Linked N-Acetylglucosamine Transferase (Ogt) for Target Gene Repression in Mouse Embryonic Stem Cells

As a member of the Tet (Ten-eleven translocation) family proteins that can convert 5-methylcytosine (5mC) to 5-hydroxylmethylcytosine (5hmC), Tet1 has been implicated in regulating global DNA demethylation and gene expression. Tet1 is highly expressed in embryonic stem (ES) cells and appears primari...

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Главные авторы: Shi, Feng-Tao, Kim, Hyeung, Lu, Weisi, He, Quanyuan, Liu, Dan, Goodell, Margaret A., Wan, Ma, Songyang, Zhou
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774349/
https://ncbi.nlm.nih.gov/pubmed/23729667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460386
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