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Mechanisms of Hippocampal Long-Term Depression Are Required for Memory Enhancement by Novelty Exploration

It is well known that novel environments can enhance learning and memory. However, the underlying mechanisms remain poorly understood. Here, we report that, in freely moving rats, novelty exploration facilitates the production of hippocampal CA1 long-term depression (LTD), a well characterized form...

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Autors principals: Dong, Zhifang, Gong, Bo, Li, Hongjie, Bai, Yanrui, Wu, Xiaoyan, Huang, Yan, He, Wenting, Li, Tingyu, Wang, Yu Tian
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774153/
https://ncbi.nlm.nih.gov/pubmed/22933783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0984-12.2012
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