Hippocampal long-term depression is required for the consolidation of spatial memory

Although NMDA receptor (NMDAR)-dependent long-term potentiation (LTP) and long-term depression (LTD) of glutamatergic transmission are candidate mechanisms for long-term spatial memory, the precise contributions of LTP and LTD remain poorly understood. Here, we report that LTP and LTD in the hippoca...

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Detalhes bibliográficos
Main Authors: Ge, Yuan, Dong, Zhifang, Bagot, Rosemary C., Howland, John G., Phillips, Anthony G., Wong, Tak Pan, Wang, Yu Tian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944752/
https://ncbi.nlm.nih.gov/pubmed/20823230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008200107
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