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Insulin receptor regulates photoreceptor CNG channel activity

Photoreceptor cyclic nucleotide gated (CNG) channels are critical elements in phototransduction and light adaptation. Here we report that insulin receptor (IR), an integral membrane protein, directly phosphorylates the CNGA1 subunit of CNG channels that in turn affects the function of these channels...

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Detalhes bibliográficos
Main Authors: Gupta, Vivek K., Rajala, Ammaji, Rajala, Raju V. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774084/
https://ncbi.nlm.nih.gov/pubmed/23032687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00199.2012
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