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Insulin receptor regulates photoreceptor CNG channel activity

Photoreceptor cyclic nucleotide gated (CNG) channels are critical elements in phototransduction and light adaptation. Here we report that insulin receptor (IR), an integral membrane protein, directly phosphorylates the CNGA1 subunit of CNG channels that in turn affects the function of these channels...

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Bibliografische gegevens
Hoofdauteurs: Gupta, Vivek K., Rajala, Ammaji, Rajala, Raju V. S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774084/
https://ncbi.nlm.nih.gov/pubmed/23032687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00199.2012
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