POLYCLONAL IMMUNE RESPONSES TO ANTIGENS ASSOCIATED WITH CANCER SIGNALING PATHWAYS AND NEW STRATEGIES TO ENHANCE CANCER VACCINES

Aberrant signaling pathways are a hallmark of cancer. A variety of strategies for inhibiting signaling pathways have been developed, but monoclonal antibodies against receptor tyrosine kinases have been amongst the most successful. A challenge for these therapies is therapeutic unresponsiveness and...

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Detalhes bibliográficos
Main Authors: Clay, Timothy M., Osada, Takuya, Hartman, Zachary C., Hobeika, Amy, Devi, Gayathri, Morse, Michael A., Lyerly, H. Kim
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774015/
https://ncbi.nlm.nih.gov/pubmed/21136201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-010-8186-6
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