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In vivo imaging of alphaherpesvirus infection reveals synchronized activity dependent on axonal sorting of viral proteins

A clinical hallmark of human alphaherpesvirus infections is peripheral pain or itching. Pseudorabies virus (PRV), a broad host range alphaherpesvirus, causes violent pruritus in many different animals, but the mechanism is unknown. Previous in vitro studies have shown that infected, cultured periphe...

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Detalhes bibliográficos
Main Authors: Granstedt, Andrea E., Bosse, Jens B., Thiberge, Stephan Y., Enquist, Lynn W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773797/
https://ncbi.nlm.nih.gov/pubmed/23980169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311062110
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