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Kinesin-3 mediates axonal sorting and directional transport of alphaherpesvirus particles in neurons

During infection of the nervous system, alphaherpesviruses, including pseudorabies virus (PRV) use retrograde axonal transport to travel towards the neuronal cell body and anterograde transport to traffic back to the cell periphery upon reactivation from latency. The PRV protein Us9 plays an essenti...

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Bibliographic Details
Main Authors: Kramer, Tal, Greco, Todd M., Taylor, Matthew P., Ambrosini, Anthony E., Cristea, Ileana M., Enquist, Lynn W.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527838/
https://ncbi.nlm.nih.gov/pubmed/23245325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.10.013
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