Remodeling nuclear architecture allows efficient transport of herpesvirus capsids by diffusion

The nuclear chromatin structure confines the movement of large macromolecular complexes to interchromatin corrals. Herpesvirus capsids of approximately 125 nm assemble in the nucleoplasm and must reach the nuclear membranes for egress. Previous studies concluded that nuclear herpesvirus capsid motil...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Bosse, Jens B., Hogue, Ian B., Feric, Marina, Thiberge, Stephan Y., Sodeik, Beate, Brangwynne, Clifford P., Enquist, Lynn W.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620878/
https://ncbi.nlm.nih.gov/pubmed/26438852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1513876112
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