Microscopy ambient ionization top-down mass spectrometry reveals developmental patterning

There is immense cellular and molecular heterogeneity in biological systems. Here, we demonstrate the utility of integrating an inverted light microscope with an ambient ionization source, nanospray electrospray desorption ionization, attached to a high-resolution mass spectrometer to characterize t...

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Main Authors: Hsu, Cheng-Chih, White, Nicholas M., Hayashi, Marito, Lin, Eugene C., Poon, Tiffany, Banerjee, Indroneal, Chen, Ju, Pfaff, Samuel L., Macagno, Eduardo R., Dorrestein, Pieter C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Physical Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773749/
https://ncbi.nlm.nih.gov/pubmed/23969833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310618110
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