The CYP2C19*17 Variant is not Independently Associated with Clopidogrel Response

BACKGROUND: Cytochrome P450 2C19 (CYP2C19) is the principle enzyme responsible for converting clopidogrel into its active metabolite and genetic variants have been identified, most notably CYP2C19*2 and CYP2C19*17, that are believed to alter its activity/expression. OBJECTIVE: We evaluated whether t...

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Bibliografiske detaljer
Main Authors: Lewis, JP, Stephens, SH, Horenstein, RB, O'Connell, JR, Ryan, K, Peer, CJ, Figg, WD., Spencer, SD, Pacanowski, MA, Mitchell, BD, Shuldiner, AR
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773276/
https://ncbi.nlm.nih.gov/pubmed/23809542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12342
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