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Evaluation of a Nanoemulsion Formulation Strategy for Oral Bioavailability Enhancement of Danazol in Rats and Dogs

The objective of this study was to determine whether nanoemulsion formulations constitute a viable strategy to improve the oral bioavailability of danazol, a compound whose poor aqueous solubility limits its oral bioavailability. Danazol-containing oil-in-water nanoemulsions (NE) with and without co...

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Main Authors: Devalapally, Harikrishna, Silchenko, Svitlana, Zhou, Feng, McDade, Jessica, Goloverda, Galina, Owen, Albert, Hidalgo, Ismael J.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773250/
https://ncbi.nlm.nih.gov/pubmed/23878097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23667
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