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Formulation and Characterization of Eplerenone Nanoemulsion Liquisolids, An Oral Delivery System with Higher Release Rate and Improved Bioavailability

Because Eplerenone (EPL) is a Biopharmaceutical Classification System (BCS) class-II drug and is prone to extensive liver degradation, it suffers from poor bioavailability after oral administration. This work aimed to prepare liquisolids loaded with EPL-nanoemulsions (EPL-NEs) that have a higher dru...

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Autor principal: Ahmed Khames
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-01-01
Colecção:Pharmaceutics
Assuntos:
Acesso em linha:http://www.mdpi.com/1999-4923/11/1/40
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