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Formulation and Characterization of Eplerenone Nanoemulsion Liquisolids, An Oral Delivery System with Higher Release Rate and Improved Bioavailability
Because Eplerenone (EPL) is a Biopharmaceutical Classification System (BCS) class-II drug and is prone to extensive liver degradation, it suffers from poor bioavailability after oral administration. This work aimed to prepare liquisolids loaded with EPL-nanoemulsions (EPL-NEs) that have a higher dru...
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Autor principal: | |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI AG
2019-01-01
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Colecção: | Pharmaceutics |
Assuntos: | |
Acesso em linha: | http://www.mdpi.com/1999-4923/11/1/40 |
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