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pH-evoked dural afferent signaling is mediated by ASIC3 and is sensitized by mast cell mediators

BACKGROUND: Prior studies have shown that decreased meningeal pH activates dural afferents via opening of acid-sensing ion channels (ASICs) suggesting one pathophysiological mechanism for the generation of headaches. The studies described here further examined the ASIC subtype mediating pH-induced d...

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Autors principals: Yan, Jin, Wei, Xiaomei, Bischoff, Christina, Edelmayer, Rebecca M., Dussor, Gregory
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773053/
https://ncbi.nlm.nih.gov/pubmed/23808707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/head.12152
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