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Activation of TRPV4 on dural afferents produces headache-related behavior in a preclinical rat model

BACKGROUND: The mechanisms contributing to the pain of migraine are poorly understood although activation of afferent nociceptors in the trigeminovascular system has been proposed as a key event. Prior studies have shown that dural-afferent nociceptors are sensitive to both osmotic and mechanical st...

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Hlavní autoři: Wei, Xiaomei, Edelmayer, Rebecca M, Yan, Jin, Dussor, Gregory
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543146/
https://ncbi.nlm.nih.gov/pubmed/22049072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0333102411427600
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