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pH-evoked dural afferent signaling is mediated by ASIC3 and is sensitized by mast cell mediators
BACKGROUND: Prior studies have shown that decreased meningeal pH activates dural afferents via opening of acid-sensing ion channels (ASICs) suggesting one pathophysiological mechanism for the generation of headaches. The studies described here further examined the ASIC subtype mediating pH-induced d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773053/ https://ncbi.nlm.nih.gov/pubmed/23808707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/head.12152 |
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