Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis

BACKGROUND AND AIM: Liver cirrhosis is associated with decreased hepatic cytochrome P4503A (CYP3A) activity but the pathogenesis of this phenomenon is not well elucidated. In this study, we examined if certain microRNAs (miRNA) are associated with decreased hepatic CYP3A activity in cirrhosis. METHO...

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Detalhes bibliográficos
Main Authors: Vuppalanchi, Raj, Liang, Tiebing, Goswami, Chirayu Pankaj, Nalamasu, Rohit, Li, Lang, Jones, David, Wei, Rongrong, Liu, Wanqing, Sarasani, Vishal, Janga, Sarath Chandra, Chalasani, Naga
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772944/
https://ncbi.nlm.nih.gov/pubmed/24058572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074471
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