Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis

BACKGROUND AND AIM: Liver cirrhosis is associated with decreased hepatic cytochrome P4503A (CYP3A) activity but the pathogenesis of this phenomenon is not well elucidated. In this study, we examined if certain microRNAs (miRNA) are associated with decreased hepatic CYP3A activity in cirrhosis. METHO...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Vuppalanchi, Raj, Liang, Tiebing, Goswami, Chirayu Pankaj, Nalamasu, Rohit, Li, Lang, Jones, David, Wei, Rongrong, Liu, Wanqing, Sarasani, Vishal, Janga, Sarath Chandra, Chalasani, Naga
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772944/
https://ncbi.nlm.nih.gov/pubmed/24058572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074471
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