Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis

BACKGROUND AND AIM: Liver cirrhosis is associated with decreased hepatic cytochrome P4503A (CYP3A) activity but the pathogenesis of this phenomenon is not well elucidated. In this study, we examined if certain microRNAs (miRNA) are associated with decreased hepatic CYP3A activity in cirrhosis. METHO...

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Bibliografiska uppgifter
Huvudupphovsmän: Vuppalanchi, Raj, Liang, Tiebing, Goswami, Chirayu Pankaj, Nalamasu, Rohit, Li, Lang, Jones, David, Wei, Rongrong, Liu, Wanqing, Sarasani, Vishal, Janga, Sarath Chandra, Chalasani, Naga
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772944/
https://ncbi.nlm.nih.gov/pubmed/24058572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074471
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