HIV-1 Nef Sequence and Functional Compartmentalization in the Gut Is Not Due to Differential Cytotoxic T Lymphocyte Selective Pressure

The gut is the largest lymphoid organ in the body and a site of active HIV-1 replication and immune surveillance. The gut is a reservoir of persistent infection in some individuals with fully suppressed plasma viremia on combination antiretroviral therapy (cART) although the cause of this persistenc...

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Detalhes bibliográficos
Main Authors: Lewis, Martha J., Frohnen, Patricia, Ibarrondo, F. Javier, Reed, Diane, Iyer, Varun, Ng, Hwee L., Elliott, Julie, Yang, Otto O., Anton, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772905/
https://ncbi.nlm.nih.gov/pubmed/24058696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075620
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