Alterations in Purkinje cell GABA(A) receptor pharmacology following oxygen and glucose deprivation and cerebral ischemia reveal novel contribution of β(1)-subunit-containing receptors

Cerebellar Purkinje cells (PCs) are particularly sensitive to cerebral ischemia, and decreased GABA(A) receptor function following injury is thought to contribute to PC sensitivity to ischemia-induced excitotoxicity. Here we examined the functional properties of the GABA(A) receptors that are spared...

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Autores principales: Kelley, Melissa H., Ortiz, Justin, Shimizu, Kaori, Grewal, Himmat, Quillinan, Nidia, Herson, Paco S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772679/
https://ncbi.nlm.nih.gov/pubmed/23176253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12064
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