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Matrix metalloproteinase-1 promotes breast cancer angiogenesis and osteolysis in a novel in vivo model

Matrix metalloproteinase-1 (MMP-1) is critical for mediating breast cancer metastasis to bone. We investigated the role of MMP-1 in breast cancer invasion of soft tissues and bone using human MDA MB-231 breast cancer cells stably transfected with shRNAs against MMP-1 and a novel murine model of bone...

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書誌詳細
主要な著者: Eck, S. M., Hoopes, P. J., Petrella, B. L., Coon, C. I., Brinckerhoff, C. E.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772530/
https://ncbi.nlm.nih.gov/pubmed/18597171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-008-0085-3
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