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Matrix metalloproteinase-1 promotes breast cancer angiogenesis and osteolysis in a novel in vivo model
Matrix metalloproteinase-1 (MMP-1) is critical for mediating breast cancer metastasis to bone. We investigated the role of MMP-1 in breast cancer invasion of soft tissues and bone using human MDA MB-231 breast cancer cells stably transfected with shRNAs against MMP-1 and a novel murine model of bone...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3772530/ https://ncbi.nlm.nih.gov/pubmed/18597171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-008-0085-3 |
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