TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses

Sepsis is a highly fatal disease caused by an initial hyperinflammatory response followed by a state of profound immunosuppression. Although it is well appreciated that the initial production of proinflammatory cytokines by macrophages accompanies the onset of sepsis, it remains unclear what causes...

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Detalhes bibliográficos
Main Authors: Cohen, Heather B., Briggs, Katharine T., Marino, John P., Ravid, Katya, Robson, Simon C., Mosser, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772500/
https://ncbi.nlm.nih.gov/pubmed/23908469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-496216
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