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IFN-γ prevents adenosine receptor (A2bR) upregulation to sustain the macrophage activation response
The priming of macrophages with IFN-γ prior to TLR stimulation results in enhanced and prolonged inflammatory cytokine production. Here, we demonstrate that following TLR stimulation, macrophages up regulate the adenosine 2b receptor (A2bR) to enhance their sensitivity to immunosuppressive extracell...
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| Publié dans: | J Immunol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4686143/ https://ncbi.nlm.nih.gov/pubmed/26355158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501139 |
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