Mast cell activation contributes to sickle cell pathobiology and pain in mice

Sickle cell anemia (SCA) is an inherited disorder associated with severe lifelong pain and significant morbidity. The mechanisms of pain in SCA remain poorly understood. We show that mast cell activation/degranulation contributes to sickle pain pathophysiology by promoting neurogenic inflammation an...

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Detaylı Bibliyografya
Asıl Yazarlar: Vincent, Lucile, Vang, Derek, Nguyen, Julia, Gupta, Mihir, Luk, Kathryn, Ericson, Marna E., Simone, Donald A., Gupta, Kalpna
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2013
Konular:
Plenary Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772495/
https://ncbi.nlm.nih.gov/pubmed/23775718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-498105
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