Ca(2+) Influx through Store-operated Ca(2+) Channels Reduces Alzheimer Disease β-Amyloid Peptide Secretion

Alzheimer disease (AD), the leading cause of dementia, is characterized by the accumulation of β-amyloid peptides (Aβ) in senile plaques in the brains of affected patients. Many cellular mechanisms are thought to play important roles in the development and progression of AD. Several lines of evidenc...

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Hlavní autoři: Zeiger, William, Vetrivel, Kulandaivelu S., Buggia-Prévot, Virginie, Nguyen, Phuong D., Wagner, Steven L., Villereal, Mitchel L., Thinakaran, Gopal
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772244/
https://ncbi.nlm.nih.gov/pubmed/23902769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.473355
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