Ca(2+) Influx through Store-operated Ca(2+) Channels Reduces Alzheimer Disease β-Amyloid Peptide Secretion

Alzheimer disease (AD), the leading cause of dementia, is characterized by the accumulation of β-amyloid peptides (Aβ) in senile plaques in the brains of affected patients. Many cellular mechanisms are thought to play important roles in the development and progression of AD. Several lines of evidenc...

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Detalhes bibliográficos
Main Authors: Zeiger, William, Vetrivel, Kulandaivelu S., Buggia-Prévot, Virginie, Nguyen, Phuong D., Wagner, Steven L., Villereal, Mitchel L., Thinakaran, Gopal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772244/
https://ncbi.nlm.nih.gov/pubmed/23902769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.473355
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