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Actin Monomers Activate Inverted Formin 2 by Competing with Its Autoinhibitory Interaction
INF2 is an unusual formin protein in that it accelerates both actin polymerization and depolymerization, the latter through an actin filament-severing activity. Similar to other formins, INF2 possesses a dimeric formin homology 2 (FH2) domain that binds filament barbed ends and is critical for polym...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3772231/ https://ncbi.nlm.nih.gov/pubmed/23921379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472415 |
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