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Mutations to the Formin Homology 2 Domain of INF2 Protein Have Unexpected Effects on Actin Polymerization and Severing

INF2 (inverted formin 2) is a formin protein with unusual biochemical characteristics. As with other formins, the formin homology 2 (FH2) domain of INF2 accelerates actin filament assembly and remains at the barbed end, modulating elongation. The unique feature of INF2 is its ability to sever filame...

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書目詳細資料
Main Authors: Ramabhadran, Vinay, Gurel, Pinar S., Higgs, Henry N.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464531/
https://ncbi.nlm.nih.gov/pubmed/22879592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365122
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