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In vitro selection of BNA (LNA) aptamers
Recently, we achieved the first in vitro selection of 2′-O,4′-C-methylene bridged/locked nucleic acid (2′,4′-BNA/LNA) aptamers. High-affinity thrombin-binding aptamers (TBAs) were obtained from DNA-based libraries containing 2′-O,4′-C-methylene-bridged/linked bicyclic ribonucleotides (B/L nucleotide...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Landes Bioscience
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3771997/ https://ncbi.nlm.nih.gov/pubmed/24044051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.25786 |
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