Differential Requirement for CCR4 in the Maintenance but Not Establishment of the Invariant Vγ5(+) Dendritic Epidermal T-Cell Pool

Thymocytes expressing the invariant Vγ5 γδT-cell receptor represent progenitors of dendritic epidermal T-cells (DETC) that play an important immune surveillance role in the skin. In contrast to the bulk of αβT-cell development, Vγ5(+) DETC progenitor development occurs exclusively in fetal thymus. W...

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Detalhes bibliográficos
Main Authors: Nakamura, Kyoko, White, Andrea J., Parnell, Sonia M., Lane, Peter J., Jenkinson, Eric J., Jenkinson, William E., Anderson, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771977/
https://ncbi.nlm.nih.gov/pubmed/24069263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074019
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