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Two tyrosine-based sorting signals in the Cx43 C-terminus cooperate to mediate gap junction endocytosis

Gap junction (GJ) channels that electrically and chemically couple neighboring cells are formed when two hemichannels (connexons) of apposed cells dock head-on in the extracellular space. Remarkably, docked connexons are inseparable under physiological conditions, and we and others have shown that G...

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Autors principals: Fong, John T., Kells, Rachael M., Falk, Matthias M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771946/
https://ncbi.nlm.nih.gov/pubmed/23885125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-02-0111
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